Elimination or reduction of risks from dangerous substances

12.—(1) Where a dangerous substance is present in or on the premises, the responsible person must ensure that risk to relevant persons related to the presence of the substance is either eliminated or reduced so far as is reasonably practicable.

(2) In complying with his duty under paragraph (1), the responsible person must, so far as is reasonably practicable, replace a dangerous substance, or the use of a dangerous substance, with a substance or process which either eliminates or reduces the risk to relevant persons.

(3) Where it is not reasonably practicable to eliminate risk pursuant to paragraphs (1) and (2), the responsible person must, so far as is reasonably practicable, apply measures consistent with the risk assessment and appropriate to the nature of the activity or operation, including the measures specified in Part 4 of Schedule 1 to this Order to—

(a)control the risk, and

(b)mitigate the detrimental effects of a fire.

(4) The responsible person must—

(a)arrange for the safe handling, storage and transport of dangerous substances and waste containing dangerous substances; and

(b)ensure that any conditions necessary pursuant to this Order for ensuring the elimination or reduction of risk are maintained.

What the Enforcement Guidance says:

Where a dangerous substance is present on premises, the responsible person must
ensure that risk related to the presence of the substance is either eliminated or reduced
so far as is reasonably practical, doing so by replacing the dangerous substance or its
use with something else that reduces the risk. Where this is not reasonably practical,
the responsible person must, as far as is reasonably practical, apply measures consistent
with the risk assessment and appropriate to the nature of the activity, in order to
control the risk and mitigate the detrimental effects of a fire.
Enforcing authorities are reminded that the coverage of the Order, including this article,
is general fire precautions (as defined) required due to the presence of a dangerous
substance. This does not extend to special technical and organisational measures
related to the reduction of risk from work processes which are dealt with under health
and safety legislation, enforced by the HSE.